Parkinsonism, a condition similar to Parkinson's disease, has a number of causes and coping strategies. Mental Adverse Drug Reactions: depression, hallucinations, confusion, delirium, memory loss, impaired thinking. Nervous System Adverse Drug Reactions: parkinsonism. 'Sinemet' is not recommended for the treatment of drug-induced extrapyramidal reactions. 'Sinemet' should be administered cautiously to patients with severe cardiovascular or pulmonary disease, bronchial asthma, renal, hepatic or endocrine disease, or history of peptic ulcer disease (because of the possibility of upper gastro-intestinal. A class of drugs used to treat mild to moderate dementia in Parkinson's disease. These drugs increase brain levels of a neurotransmitter called acetylcholine, which helps neurons communicate with each other and is involved in memory, learning and thinking. INTRODUCTION. Motor fluctuations and dyskinesia are important complications of levodopa therapy that affect many patients with advancing Parkinson disease (PD). Dopaminergic antiparkinsonism agents aim to replace dopamine or prevent the degradation of dopamine. Antiparkinson drugs that aim to replace dopamine in the central nervous system, either release dopamine or mimic the action of dopamine. Learn about Sinemet (Carbidopa-Levodopa) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Ocular symptoms include decreased color discrimination and contrast sensitivity, visual hallucinations, reduced blinking and other problems with eyelid movement, and multistep saccades,(Biousseet al, 2004). Neuroleptics Medication-induced movement disorders caused by neuroleptics are divided into three time periods. The early-onset type, which usually occurs within the first seven days of treatment with neuroleptics, is known as neuroleptic-induced acute dystonia. Sinemet ® (carbidopa levodopa) is a combination of carbidopa and levodopa for the treatment of Parkinson's disease and syndrome. Carbidopa, an inhibitor of aromatic amino acid decarboxylation, is a white, crystalline compound, slightly soluble in water, with a molecular weight of 244.3.